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Designing Stationary Phases for Improved Protein Separations- [electronic resource]
Designing Stationary Phases for Improved Protein Separations- [electronic resource]
- 자료유형
- 학위논문
- Control Number
- 0016932743
- International Standard Book Number
- 9798379838713
- Dewey Decimal Classification Number
- 616
- Main Entry-Personal Name
- Wagner, Tyrel.
- Publication, Distribution, etc. (Imprint
- [S.l.] : Purdue University., 2022
- Publication, Distribution, etc. (Imprint
- Ann Arbor : ProQuest Dissertations & Theses, 2022
- Physical Description
- 1 online resource(89 p.)
- General Note
- Source: Dissertations Abstracts International, Volume: 85-01, Section: B.
- General Note
- Advisor: Wirth, Mary.
- Dissertation Note
- Thesis (Ph.D.)--Purdue University, 2022.
- Restrictions on Access Note
- This item must not be sold to any third party vendors.
- Summary, Etc.
- 요약As monoclonal antibodies (mAbs) become a more important part of the pharmaceutical industry, the need for better quicker analysis of then will also increase. To do this, better stationary phases specifically designed for mAbs need to be developed to analyze the quality of mAbs by their critical control attributes. The three main critical control attributes are size, charge, and glycosylation. This work focuses mainly on the development of stationary phases to analyze critical control attributes in size and charge through using a non-porous silica base and surface confined atom transfer radical polymerization to grow improved stationary phases that minimize undesired interactions and maximize desired interactions.
- Subject Added Entry-Topical Term
- Hemodialysis.
- Subject Added Entry-Topical Term
- Monoclonal antibodies.
- Subject Added Entry-Topical Term
- Mass spectrometry.
- Subject Added Entry-Topical Term
- Glycoproteins.
- Subject Added Entry-Topical Term
- Electrodes.
- Subject Added Entry-Topical Term
- Flow velocity.
- Subject Added Entry-Topical Term
- Solvents.
- Subject Added Entry-Topical Term
- Electric fields.
- Subject Added Entry-Topical Term
- Polymerization.
- Subject Added Entry-Topical Term
- Amino acids.
- Subject Added Entry-Topical Term
- Molecular weight.
- Subject Added Entry-Topical Term
- Scientific imaging.
- Subject Added Entry-Topical Term
- Chemical bonds.
- Subject Added Entry-Topical Term
- Biosensors.
- Subject Added Entry-Topical Term
- Chromatography.
- Subject Added Entry-Topical Term
- Antigens.
- Subject Added Entry-Topical Term
- Pore size.
- Subject Added Entry-Topical Term
- Ammonia.
- Subject Added Entry-Topical Term
- Analytical chemistry.
- Subject Added Entry-Topical Term
- Chemistry.
- Subject Added Entry-Topical Term
- Electromagnetics.
- Subject Added Entry-Topical Term
- Fluid mechanics.
- Subject Added Entry-Topical Term
- Mechanics.
- Subject Added Entry-Topical Term
- Medicine.
- Subject Added Entry-Topical Term
- Pharmaceutical sciences.
- Subject Added Entry-Topical Term
- Physics.
- Added Entry-Corporate Name
- Purdue University.
- Host Item Entry
- Dissertations Abstracts International. 85-01B.
- Host Item Entry
- Dissertation Abstract International
- Electronic Location and Access
- 로그인을 한후 보실 수 있는 자료입니다.
- Control Number
- joongbu:643548
