자료유형  

 학위논문

Control Number  

0016933745

International Standard Book Number  

9798380259026

Dewey Decimal Classification Number  

612

Main Entry-Personal Name  

Harris, Rebekah J.

Publication, Distribution, etc. (Imprint  

[S.l.] : University of Pittsburgh., 2021

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2021

Physical Description  

1 online resource(270 p.)

General Note  

Source: Dissertations Abstracts International, Volume: 85-03, Section: B.

General Note  

Advisor: Kwoh, CKent;Boudreau, Robert;Brach, Jennifer;Strotmeyer, Elsa;Cauley, Jane.

Dissertation Note  

Thesis (Ph.D.)--University of Pittsburgh, 2021.

Restrictions on Access Note  

This item must not be sold to any third party vendors.

Summary, Etc.  

요약Background:Knee osteoarthritis is the most prevalent type of osteoarthritis (OA) and a leading cause of disability in the United States. Falls are a major cause of morbidity and mortality in older adults. Our aim is to examine how the severity of radiographic OA impacts recurrent falls in a cohort of middle and older aged individuals enrolled in the Osteoarthritis Initiative (OAI).Methods:3,972 participants, mean age of 63 years, 58% female were assessed for worst severity of knee OA (KOA) from baseline to 36 months. Participant characteristics were summarized by worst OA severity with appropriate descriptive statistics. We used generalized estimating equations for repeated logistic regression to model the association between KOA severity and the likelihood of recurrent falls over follow-up of 5 years.Results:Older adults (≥age 65) with KOA were at higher odds of recurrent falls in comparison to individuals without KOA in models adjusting for known covariates (possible OA OR= 2.22, 95% CI= 1.09-4.52; mild OA OR=2.48, 95% CI= 1.34-4.62; unilateral moderate-severe OA OR= 2.84, 95% CI= 1.47- 5.50; bilateral moderate-severe OA OR= 2.52, 95% CI= 1.13-5.62). Middle aged adults with KOA did not have increased odds of recurrent falls in comparison to those without KOA except for possible KOA (OR= 1.86, 95% CI=1.01-2.78) (KLseverity*age interaction = 0.025).Conclusions:Older adults with radiographic evidence of KOA have an increased likelihood of experiencing recurrent falls in comparison to their counterparts without KOA independent of known risk factors. Results suggest fall prevention efforts should include older adults with all stages of KOA.

Subject Added Entry-Topical Term  

Body fat.

Subject Added Entry-Topical Term  

Womens health.

Subject Added Entry-Topical Term  

Demography.

Subject Added Entry-Topical Term  

Older people.

Subject Added Entry-Topical Term  

Body mass index.

Subject Added Entry-Topical Term  

Epidemiology.

Subject Added Entry-Topical Term  

Health care.

Subject Added Entry-Topical Term  

Aging.

Subject Added Entry-Topical Term  

Gerontology.

Subject Added Entry-Topical Term  

Health sciences.

Subject Added Entry-Topical Term  

Public health.

Subject Added Entry-Topical Term  

Sociology.

Added Entry-Corporate Name  

University of Pittsburgh.

Host Item Entry  

Dissertations Abstracts International. 85-03B.

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:641451