자료유형  

 학위논문

Control Number  

0016935348

International Standard Book Number  

9798380614061

Dewey Decimal Classification Number  

157

Main Entry-Personal Name  

Herzog, Musya.

Publication, Distribution, etc. (Imprint  

[S.l.] : Columbia University., 2023

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2023

Physical Description  

1 online resource(98 p.)

General Note  

Source: Dissertations Abstracts International, Volume: 85-04, Section: B.

General Note  

Advisor: Verdeli, Lena.

Dissertation Note  

Thesis (Ph.D.)--Columbia University, 2023.

Restrictions on Access Note  

This item must not be sold to any third party vendors.

Summary, Etc.  

요약A neuropsychological examination is often used in tandem with other measures to confirm the diagnosis of idiopathic Normal Pressure Hydrocephalus (iNPH) and to assess improvement in cognitive functioning after a lumbar puncture test. Improvement in symptoms is thought to predict benefit from installation of a ventriculoperitoneal shunt that redirects CSF from the brain. Although the 72-hour external lumbar drain (ELD) has long been the gold-standard drainage procedure, hospitals are increasingly opting for the high-volume lumbar puncture, during which 50ml of CSF is released over an hour before the patient is tested for improvement in symptoms. The primary aims of this study were to evaluate the changes in cognitive performance produced by the two LP procedures and to compare the results produced by each procedure. In a review of medical records, 40 patients met criteria for inclusion. Cognitive functioning in the 72-hour ELD (n = 10) group was compared to changes in patients in the HVLP group, in terms of baseline level of functioning and post-drain changes. Statistical methods used to determine change included ANOVA and Reliable Change Indices. Dominant-hand Grooved Pegboard Test showed significant change after lumbar puncture, with higher mean change in the 72-hour ELD group. 72-hour ELD patients had a slightly higher rate of Reliable Change than HVLP patients. Cognitive changes were bi-directional in both groups. Results suggest that changes in cognitive functioning after lumbar puncture occur in a minority of patients, regardless of procedure type, and may have low predictive value for VPS benefit.

Subject Added Entry-Topical Term  

Clinical psychology.

Subject Added Entry-Topical Term  

Cognitive psychology.

Subject Added Entry-Topical Term  

Neurosciences.

Index Term-Uncontrolled  

Neuropsychology

Index Term-Uncontrolled  

Normal Pressure Hydrocephalus

Index Term-Uncontrolled  

External lumbar drain

Index Term-Uncontrolled  

Lumbar puncture

Added Entry-Corporate Name  

Columbia University Psychology

Host Item Entry  

Dissertations Abstracts International. 85-04B.

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:639371