Material Type  

 학위논문

 

0017162652

Date and Time of Latest Transaction  

20250211152037

ISBN  

9798383202074

DDC  

150

Author  

Currin, Danielle Leigh.

Title/Author  

Anhedonia as a Transdiagnostic Symptom: Implications for Cognition and White Matter Development.

Publish Info  

[S.l.] : University of California, Los Angeles., 2024

Publish Info  

Ann Arbor : ProQuest Dissertations & Theses, 2024

Material Info  

93 p.

General Note  

Source: Dissertations Abstracts International, Volume: 86-01, Section: B.

General Note  

Advisor: Karlsgodt, Katherine H.

학위논문주기  

Thesis (Ph.D.)--University of California, Los Angeles, 2024.

Abstracts/Etc  

요약Anhedonia is a transdiagnostic symptom characterized by the loss of the experience of pleasure from typically enjoyable activities. An established body of research has explored the impact of anhedonia on functioning and long-term outcomes in psychiatric populations, and emerging research has examined the role of anhedonia in adolescents with no psychiatric diagnosis. Anhedonia has been found to impact goal-directed behavior, reward processing, and future-oriented thinking. These behaviors are associated with cognitive abilities, which include both "hot" and "cold" cognition. These two cognitive systems develop throughout adolescence and are impacted in numerous psychiatric disorders. However, existing work has not provided a clear picture of how these pieces - anhedonia, adolescent development, and cognitive systems - fit together across diagnostic categories.The goal of this dissertation, which comprises three studies, was to bridge this gap by providing an in-depth look at anhedonia across adolescence and early adulthood using a dimensional lens and multiple modalities, including self-report, task performance, and brain imaging. In Study 1, I investigated associations between subcategories of anhedonia and aspects of risk-taking behavior in university students using hierarchical linear regression. Individuals who experienced less anticipatory pleasure (i.e., looking forward to an activity) engaged in more risk-taking behavior. In Study 2, I expanded these findings by investigating relationships among anhedonia, risk-taking behavior, risk perception, and working memory in adolescents across a wider age range using linear regression and a moderation analysis. I replicated the positive association between anhedonia and risk-taking behavior and found a positive relationship between age and working memory performance. The hypothesized moderation model was not significant. In Study 3, I examined the associations among psychosis diagnosis, anhedonia, and white matter integrity in adolescents using linear regression and a linear mixed model. I found a significant group difference in a frontrostriatal tract associated with "hot" cognition, and a significant negative relationship between anhedonia and integrity in a white matter bundle associated with "cold" cognition. I highlight the need to continue exploring relationships among anhedonia, cognition, and white matter in adolescence. The implications of this work, including further illumination of the impact of anhedonia on functioning across diagnoses, are also discussed.

Subject Added Entry-Topical Term  

Psychology.

Subject Added Entry-Topical Term  

Mental health.

Subject Added Entry-Topical Term  

Cognitive psychology.

Subject Added Entry-Topical Term  

Clinical psychology.

Index Term-Uncontrolled  

Anhedonia

Index Term-Uncontrolled  

Transdiagnostic symptom

Index Term-Uncontrolled  

Cognition

Index Term-Uncontrolled  

White matter development

Index Term-Uncontrolled  

Psychiatric disorders

Added Entry-Corporate Name  

University of California, Los Angeles Psychology 0780

Host Item Entry  

Dissertations Abstracts International. 86-01B.

Electronic Location and Access  

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Control Number  

joongbu:658182