자료유형  

 학위논문

Control Number  

0017160609

International Standard Book Number  

9798382321387

Dewey Decimal Classification Number  

617

Main Entry-Personal Name  

Sherman, Josiah.

Publication, Distribution, etc. (Imprint  

[S.l.] : Yale University., 2024

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2024

Physical Description  

117 p.

General Note  

Source: Dissertations Abstracts International, Volume: 85-11, Section: B.

Dissertation Note  

Thesis (M.D.)--Yale University, 2024.

Summary, Etc.  

요약INTRODUCTION: Artificial intelligence (AI) and machine learning (ML) techniques have become highly visible in society and medicine, with some AI/ML-enabled devices receiving approval by the Federal Drug Administration for use in direct patient care. In neurosurgery, ML algorithms have been developed for clinical outcome prediction, many of which have achieved higher predictive ability than standard statistical analysis techniques. However, few have synthesized the ML literature in neurosurgery and its subspecialties. Given the rapid rate at which ML algorithms for outcome prediction and prognostication have developed in neurosurgery, additional synthesis of the current ML landscape in this area is necessary. The aim of this study was to perform a rapid review of PubMed-indexed neurosurgery literature concerning the development, validation, and/or use of ML algorithms for clinical outcome prediction.METHODS: Studies describing the development, validation, and/or use of ML algorithms for clinical outcome prediction published through October 15, 2023 in 14 prominent neurosurgery journals were identified via PubMed. Articles were screened by title and abstract. Manuscripts passing title-abstract screening were manually reviewed for inclusion. Studies were placed into groups based on subspeciality. Studies concerning the use of ML for radiomics were excluded.RESULTS: A total of 741 articles were identified from the initial PubMed query. Of these articles, 247 articles (33.3%) passed title-abstract screening. Of the articles that passed initial screening, 202 were included (27.3% of original 741 articles; 81.8% of articles that passed title-abstract screening). Of the 202 articles that passed both initial title-abstract screening and manuscript review, 114 (56.4%) were in the Spine cohort, 29 (14.4%) were in the Neuro-Oncology cohort, 7 (3.5%) were in the Pediatric Neurosurgery cohort, 31 (15.3%) were in the Cerebrovascular Neurosurgery cohort, 4 (2.0%) were in the Epilepsy/Functional Neurosurgery cohort, 12 (5.9%) were in the Trauma cohort, and 5 (2.5%) were in the Other cohort. External validation was performed in 22 studies (10.9%). Many reported algorithms achieved high model performance for clinical outcome prediction in neurosurgery and its subspecialties.CONCLUSION: The ML literature for clinical outcome precision in neurosurgery has grown rapidly in recent years. Few articles report external validation of developed ML algorithms, limiting their generalizability and clinical practicality. Future ML algorithms developed for clinical outcome prediction in neurosurgery should perform external validation of developed ML models.

Subject Added Entry-Topical Term  

Surgery.

Subject Added Entry-Topical Term  

Neurosciences.

Index Term-Uncontrolled  

ML algorithms

Index Term-Uncontrolled  

Machine learning

Index Term-Uncontrolled  

Neurosurgery

Index Term-Uncontrolled  

Outcome prediction

Index Term-Uncontrolled  

Risk prediction

Added Entry-Personal Name  

DiLuna, Michael

Added Entry-Corporate Name  

Yale University Yale School of Medicine

Host Item Entry  

Dissertations Abstracts International. 85-11B.

Electronic Location and Access  

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Control Number  

joongbu:658096