자료유형  

 학위논문

Control Number  

0016933872

International Standard Book Number  

9798380121170

Dewey Decimal Classification Number  

620.11

Main Entry-Personal Name  

Vreeman, Gerrit.

Publication, Distribution, etc. (Imprint  

[S.l.] : University of Minnesota., 2023

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2023

Physical Description  

1 online resource(191 p.)

General Note  

Source: Dissertations Abstracts International, Volume: 85-02, Section: B.

General Note  

Advisor: Sun, Changquan Calvin.

Dissertation Note  

Thesis (Ph.D.)--University of Minnesota, 2023.

Restrictions on Access Note  

This item must not be sold to any third party vendors.

Summary, Etc.  

요약Powder compaction plays a large role in many industries, including pharmaceutical tablet, metal part, detergent, cosmetics, and food manufacturing. Assessing the mechanical properties of a powdered material is an important step in developing processes that can effectively transform a powdered material into a product via densification. In-die analyses performed during compaction are fast and materials sparing compared to traditional out-of-die approaches. The goal of this work includes: (1) evaluate the effectiveness of fast, materials- sparing in-die methods for characterizing powder compaction compared to traditional out- of-die methods; (2) explore the benefits of using in-die elastic recovery measures to predict compact lamination via air entrapment; and (3) develop a universal compressibility model framework that can fully describe in-die compaction data, including all low- and high-pressure mechanisms. These goals aim to enable a fast and materials-sparing assessment of powder mechanical properties and lays a foundation for optimal formulation composition, processing strategy, and quality control assessment from such mechanical property assessments.

Subject Added Entry-Topical Term  

Pharmaceutical sciences.

Subject Added Entry-Topical Term  

Materials science.

Subject Added Entry-Topical Term  

Industrial engineering.

Index Term-Uncontrolled  

Compaction characterization

Index Term-Uncontrolled  

Compressibility

Index Term-Uncontrolled  

Elasticity

Index Term-Uncontrolled  

Powder compression

Index Term-Uncontrolled  

Powder plasticity

Index Term-Uncontrolled  

Tablet

Added Entry-Corporate Name  

University of Minnesota Pharmaceutics

Host Item Entry  

Dissertations Abstracts International. 85-02B.

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:642012