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Combining Mixed Effects Modeling with Sparse Regression for Model Selection Using Biological Time Series Data- [electronic resource]
Combining Mixed Effects Modeling with Sparse Regression for Model Selection Using Biological Time Series Data- [electronic resource]
- 자료유형
- 학위논문
- Control Number
- 0016932879
- International Standard Book Number
- 9798379868956
- Dewey Decimal Classification Number
- 333.9516
- Main Entry-Personal Name
- Rich, Sabina.
- Publication, Distribution, etc. (Imprint
- [S.l.] : North Carolina State University., 2022
- Publication, Distribution, etc. (Imprint
- Ann Arbor : ProQuest Dissertations & Theses, 2022
- Physical Description
- 1 online resource(146 p.)
- General Note
- Source: Dissertations Abstracts International, Volume: 85-01, Section: B.
- General Note
- Advisor: Tran, Hien;Lloyd, Alun;Kennedy-Stoskopf, Suzanne;Flores, Kevin.
- Dissertation Note
- Thesis (Ph.D.)--North Carolina State University, 2022.
- Restrictions on Access Note
- This item must not be sold to any third party vendors.
- Summary, Etc.
- 요약By using the population level data of heterogeneous populations, statistical and mathematical approaches, such as Lasso and mixed effects modeling, to identify variables of interest and find a model that would fit different populations. The heterogeneity of the populations is exhibited in observational data on bonobos and simulated data involving oncology patients and the subsequent tumor dynamics. The results show that it is feasible to identify, and feature select variables that are of importance. In the bonobo dataset, sex, age and cardiac medication were consistent indicators and in the tumor dynamics, the growth and decay constants showed as central to understanding the subtleties of the tumor growth. This work sends a clear message that application of these methodologies can be extended to a variety of datasets in diverse research fields.
- Subject Added Entry-Topical Term
- Endangered & extinct species.
- Subject Added Entry-Topical Term
- Wildlife conservation.
- Added Entry-Corporate Name
- North Carolina State University.
- Host Item Entry
- Dissertations Abstracts International. 85-01B.
- Host Item Entry
- Dissertation Abstract International
- Electronic Location and Access
- 로그인을 한후 보실 수 있는 자료입니다.
- Control Number
- joongbu:641922