자료유형  

 학위논문

Control Number  

0016932744

International Standard Book Number  

9798379842093

Dewey Decimal Classification Number  

545

Main Entry-Personal Name  

Szalwinski, Lucas J.

Publication, Distribution, etc. (Imprint  

[S.l.] : Purdue University., 2022

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2022

Physical Description  

1 online resource(223 p.)

General Note  

Source: Dissertations Abstracts International, Volume: 85-01, Section: B.

General Note  

Advisor: Cooks, R. Graham.

Dissertation Note  

Thesis (Ph.D.)--Purdue University, 2022.

Restrictions on Access Note  

This item must not be sold to any third party vendors.

Summary, Etc.  

요약Mass spectrometry has become the premium chemical identification method. The next advancement for mass spectrometry is the widespread use of mass spectrometers for on-site chemical/biological identification. Ion trap mass spectrometers have emerged as powerful on-site analytical platforms, in spite of limited mass resolution, due to their compatibility with ambient ionization methods and ready implementation of tandem mass spectrometry (MS/MS). However, conventionally operated ion traps are inefficient in accessing the entire tandem mass spectrometry dataspace. By operating the ion trap at a constant trapping voltage, more efficient tandem mass spectrometry scan modes are accessible. The most efficient is to acquire the entire tandem mass spectrometry data space and this work demonstrates three different methods of acquiring this data domain. These methods acquire the data in under a second and the best performing method was implemented in a miniature mass spectrometer without performance decrease. The impact of this device is most powerful when analysis requires the entire ionized sample be considered to determine the identity of the sample. This was shown to be useful for monitoring the lipid metabolism in a model microorganism.

Subject Added Entry-Topical Term  

Mass spectrometry.

Subject Added Entry-Topical Term  

Heroin.

Subject Added Entry-Topical Term  

Ecstasy.

Subject Added Entry-Topical Term  

Fourier transforms.

Subject Added Entry-Topical Term  

Ions.

Subject Added Entry-Topical Term  

Sensors.

Subject Added Entry-Topical Term  

Fatty acids.

Subject Added Entry-Topical Term  

Cocaine.

Subject Added Entry-Topical Term  

Scientific imaging.

Subject Added Entry-Topical Term  

Chemicals.

Subject Added Entry-Topical Term  

E coli.

Subject Added Entry-Topical Term  

Lipids.

Subject Added Entry-Topical Term  

Methamphetamine.

Subject Added Entry-Topical Term  

Fentanyl.

Subject Added Entry-Topical Term  

Amphetamines.

Subject Added Entry-Topical Term  

Onsite.

Subject Added Entry-Topical Term  

Analytical chemistry.

Subject Added Entry-Topical Term  

Chemistry.

Subject Added Entry-Topical Term  

Mathematics.

Added Entry-Corporate Name  

Purdue University.

Host Item Entry  

Dissertations Abstracts International. 85-01B.

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:641593