자료유형  

 학위논문

Control Number  

0016931130

International Standard Book Number  

9798380605922

Dewey Decimal Classification Number  

636

Main Entry-Personal Name  

Wells, Teri L.

Publication, Distribution, etc. (Imprint  

[S.l.] : University of Florida., 2022

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2022

Physical Description  

1 online resource(130 p.)

General Note  

Source: Dissertations Abstracts International, Volume: 85-04, Section: B.

General Note  

Advisor: Nelson, Corwin D.

Dissertation Note  

Thesis (Ph.D.)--University of Florida, 2022.

Restrictions on Access Note  

This item must not be sold to any third party vendors.

Summary, Etc.  

요약The overall objectives of this dissertation were to study how nutrients, specifically vitamin D, and social grouping contributes to the immune function, health, growth and development of dairy cattle. Chapter 1 reviews the literature on the mastitis and heifer development and roles of vitamin D and calf housing on dairy calf development and immunity. Chapters 2 and 3 pertain to the effects of intramammary vitamin D treatments. Chapter 2 reports the results of testing the effect of dose and source of intramammary vitamin D treatments on gene expression and serum calcium. The work from Chapter 2 shows that 500 ug intramammary calcidiol (25-hydroxyvitamin D3) influenced milk cell gene expression without affecting serum Ca; whereas 50 ug calcitriol (1,25-dihydroxyvitamin D3) influenced milk cell gene expression but also increased serum Ca.Chapter 3 reports the effectiveness of intramammary vitamin D as a treatment for mastitis in dairy cattle. Calcitriol treatment administered at the onset of mastitis symptoms decreased the percentages of CD11b+CD14-(neutrophils) and concentrations of 8-iso-15R isoprostane in milk of infected quarters compared with placebo. Calcitriol did not affect bacteria or somatic cell 13counts in milk. The intramammary calcitriol treatment was not able to remove the S. uberis infection. Chapters 4 and 5 focus on heifer calf growth and immunity. Chapter 4 presents the effects of dietary calcidiol (1.7 ug/kg BW) on growth, health, and performance of dairy heifers until 3 months of age. Supplementing dietary calcidiol increased average body weight by 4 kg at weaning compared to control heifers possibly due to increased milk intake. Calcidiol decreased the concentration of monocytes in blood. Chapter 5 reports the effect of dairy calf housing on calf performance and immune competence. Housing treatments had no effect on calf body weights or average daily gain at weaning. Granulocyte percentage was decreased in GH calves indicating lower presence of infection. The concentration of CD T cells in blood was influenced by the interaction of social housing by age. Cell-mediated ex vivo recall responses to C. Albicans were influenced by social housing. Likewise, antibody-mediated responses to Keyhole limpet hemocyanin were influenced by the interaction of social hosing and age. Altogether, vitamin D nutrition and social housing are factors in immune development of dairy calves.

Subject Added Entry-Topical Term  

Animal sciences.

Subject Added Entry-Topical Term  

Genetics.

Subject Added Entry-Topical Term  

Immunology.

Subject Added Entry-Topical Term  

Nutrition.

Index Term-Uncontrolled  

Animal welfare

Index Term-Uncontrolled  

Dairy cattle

Index Term-Uncontrolled  

Mammary gland immunity

Index Term-Uncontrolled  

Social housing

Index Term-Uncontrolled  

Vitamin D treatments

Added Entry-Corporate Name  

University of Florida Animal Sciences

Host Item Entry  

Dissertations Abstracts International. 85-04B.

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:639896