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Boston University Henry M. Goldman School of Dental Medicine
Boston University Henry M. Goldman School of Dental Medicine

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자료유형  
 학위논문
Control Number  
0014999172
International Standard Book Number  
9780438041981
Dewey Decimal Classification Number  
617.6
Main Entry-Personal Name  
Alwafi, Hanadi A.
Publication, Distribution, etc. (Imprint  
[Sl] : Boston University, 2018
Publication, Distribution, etc. (Imprint  
Ann Arbor : ProQuest Dissertations & Theses, 2018
Physical Description  
230 p
General Note  
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
General Note  
Adviser: Laisheng Chou.
Dissertation Note  
Thesis (D.Sc.D.)--Boston University, 2018.
Summary, Etc.  
요약Background: Thymoquinone (TQ) is one of the most active ingredients of Nigella sativa seed. TQ has a variety of pharmacologic properties including possess antinociceptive, antibacterial, anti-inflammatory, anti-oxidative activities and osteogeni
Summary, Etc.  
요약Purpose: This study evaluates the effect of TQ on the attachment efficiency, proliferation, and odontogenic differentiation of Human Dental Pulp Cells (HDPC's). The effect of TQ on odontogenic differentiation was also determined by evaluating al
Summary, Etc.  
요약Methods: Human dental pulp cells were cultured in triplicate using growth media with various TQ concentrations: 5 muM, 10muM, 15muM, 30muM, and 10muM as a control group at 7 and 21 days. Crystal violet staining was used to determine cell attachm
Summary, Etc.  
요약Results: Higher cell attachment efficiency was shown in all TQ groups at 16 hours (P. 0001) except for the 5 muM group. A significantly higher cell proliferation rate was shown with low TQ concentration 5 muM at 7 days (P. 0001) and at 21days
Summary, Etc.  
요약Conclusion: All tested TQ concentrations significantly enhanced cell attachment efficiency at 16 hours except TQ =5 muM. Cell proliferation rates were increased significantly by low TQ concentration 5 muM, and decreased significantly with higher
Subject Added Entry-Topical Term  
Dentistry
Subject Added Entry-Topical Term  
Biology
Added Entry-Corporate Name  
Boston University Pediatric Dentistry GSDM
Host Item Entry  
Dissertation Abstracts International. 79-10B(E).
Host Item Entry  
Dissertation Abstract International
Electronic Location and Access  
로그인을 한후 보실 수 있는 자료입니다.
Control Number  
joongbu:557351

MARC

 008181129s2018                                          c    eng  d
■001000014999172
■00520190102172256
■020    ▼a9780438041981
■035    ▼a(MiAaPQ)AAI10828486
■035    ▼a(MiAaPQ)bu:13980
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a617.6
■1001  ▼aAlwafi,  Hanadi  A.
■24510▼aBoston  University  Henry  M.  Goldman  School  of  Dental  Medicine
■260    ▼a[Sl]▼bBoston  University▼c2018
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2018
■300    ▼a230  p
■500    ▼aSource:  Dissertation  Abstracts  International,  Volume:  79-10(E),  Section:  B.
■500    ▼aAdviser:  Laisheng  Chou.
■5021  ▼aThesis  (D.Sc.D.)--Boston  University,  2018.
■520    ▼aBackground:  Thymoquinone  (TQ)  is  one  of  the  most  active  ingredients  of  Nigella  sativa  seed.  TQ  has  a  variety  of  pharmacologic  properties  including  possess  antinociceptive,  antibacterial,  anti-inflammatory,  anti-oxidative  activities  and  osteogeni
■520    ▼aPurpose:  This  study  evaluates  the  effect  of  TQ  on  the  attachment  efficiency,  proliferation,  and  odontogenic  differentiation  of  Human  Dental  Pulp  Cells  (HDPC's).  The  effect  of  TQ  on  odontogenic  differentiation  was  also  determined  by  evaluating  al
■520    ▼aMethods:  Human  dental  pulp  cells  were  cultured  in  triplicate  using  growth  media  with  various  TQ  concentrations:  5  muM,  10muM,  15muM,  30muM,  and  10muM  as  a  control  group  at  7  and  21  days.  Crystal  violet  staining  was  used  to  determine  cell  attachm
■520    ▼aResults:  Higher  cell  attachment  efficiency  was  shown  in  all  TQ  groups  at  16  hours  (P.  0001)  except  for  the  5  muM  group.  A  significantly  higher  cell  proliferation  rate  was  shown  with  low  TQ  concentration  5  muM  at  7  days  (P.  0001)  and  at  21days  
■520    ▼aConclusion:  All  tested  TQ  concentrations  significantly  enhanced  cell  attachment  efficiency  at  16  hours  except  TQ  =5  muM.  Cell  proliferation  rates  were  increased  significantly  by  low  TQ  concentration  5  muM,  and  decreased  significantly  with  higher
■590    ▼aSchool  code:  0017.
■650  4▼aDentistry
■650  4▼aBiology
■690    ▼a0567
■690    ▼a0306
■71020▼aBoston  University▼bPediatric  Dentistry  GSDM.
■7730  ▼tDissertation  Abstracts  International▼g79-10B(E).
■773    ▼tDissertation  Abstract  International
■790    ▼a0017
■791    ▼aD.Sc.D.
■792    ▼a2018
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T14999172▼nKERIS
■980    ▼a201812▼f2019

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