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Integrating Genetics into Population-based Studies
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Integrating Genetics into Population-based Studies
자료유형  
 학위논문
Control Number  
0014998678
International Standard Book Number  
9780438250161
Dewey Decimal Classification Number  
614.4
Main Entry-Personal Name  
Tai, Caroline G.
Publication, Distribution, etc. (Imprint  
[Sl] : University of California, San Francisco, 2018
Publication, Distribution, etc. (Imprint  
Ann Arbor : ProQuest Dissertations & Theses, 2018
Physical Description  
104 p
General Note  
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
General Note  
Adviser: John S. Witte.
Dissertation Note  
Thesis (Ph.D.)--University of California, San Francisco, 2018.
Summary, Etc.  
요약As genotyping has become more affordable, there has been a growing effort to leverage genetic data to improve our understanding of the determinants of disease at the population level. New challenges arise with more widespread use of genetic data
Summary, Etc.  
요약This dissertation was comprised of three projects that showcase important topics for epidemiologists to consider when using genetic data. These include developing genetic risk scores, determining the analysis method most suitable for the availab
Summary, Etc.  
요약The first chapter explores differential genetic susceptibility between aggressive and non-aggressive prostate cancer and whether these differences can be used to develop a polygenic risk score for disease aggressiveness. This study was conducted
Summary, Etc.  
요약The lessons learned from this dissertation provide evidence that genetic data allows for exploration of inherited susceptibilities that can influence risk of disease but care must be taken to understand which groups of individuals should be comp
Subject Added Entry-Topical Term  
Epidemiology
Subject Added Entry-Topical Term  
Genetics
Added Entry-Corporate Name  
University of California, San Francisco Epidemiology and Translational Science
Host Item Entry  
Dissertation Abstracts International. 79-12B(E).
Host Item Entry  
Dissertation Abstract International
Electronic Location and Access  
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Control Number  
joongbu:556926
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