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Movement of the Escherichia coli RNA Polymerase Clamp Modulates Intrinsic Transcription Termination
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Movement of the Escherichia coli RNA Polymerase Clamp Modulates Intrinsic Transcription Termination
자료유형  
 학위논문
Control Number  
0015001161
International Standard Book Number  
9780438357532
Dewey Decimal Classification Number  
574
Main Entry-Personal Name  
Bellecourt, Michael J.
Publication, Distribution, etc. (Imprint  
[Sl] : The University of Wisconsin - Madison, 2018
Publication, Distribution, etc. (Imprint  
Ann Arbor : ProQuest Dissertations & Theses, 2018
Physical Description  
180 p
General Note  
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
General Note  
Adviser: Robert C. Landick.
Dissertation Note  
Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018.
Summary, Etc.  
요약Cellular organisms use RNA polymerases (RNAPs) to express genes through the process of transcription. Accurate and timely RNA synthesis requires regulation of all steps of a complex transcription cycle, a regulatory framework involving the caref
Summary, Etc.  
요약Prior to my studies, the role of nucleic-acid sequence and structure in these mechanisms were well-characterized, but the role of protein conformation changes were largely unknown. To investigate how movements by the RNAP clamp affected intrinsi
Summary, Etc.  
요약My studies also determined how the transcription factor NusG promotes Rho-dependent termination. After binding C-rich RNAs in its secondary site, the Rho ring makes small amino acid rearrangements in its C-terminal domain to induce ring closure.
Subject Added Entry-Topical Term  
Biochemistry
Subject Added Entry-Topical Term  
Molecular biology
Subject Added Entry-Topical Term  
Microbiology
Added Entry-Corporate Name  
The University of Wisconsin - Madison Biochemistry-ALS
Host Item Entry  
Dissertation Abstracts International. 80-01B(E).
Host Item Entry  
Dissertation Abstract International
Electronic Location and Access  
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Control Number  
joongbu:554910
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