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Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2
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Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2
자료유형  
 학위논문
Control Number  
0014999730
International Standard Book Number  
9780438271593
Dewey Decimal Classification Number  
574
Main Entry-Personal Name  
Turton, Keren B.
Publication, Distribution, etc. (Imprint  
[Sl] : The University of Wisconsin - Madison, 2018
Publication, Distribution, etc. (Imprint  
Ann Arbor : ProQuest Dissertations & Theses, 2018
Physical Description  
263 p
General Note  
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
General Note  
Adviser: Deane F. Mosher.
Dissertation Note  
Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018.
Summary, Etc.  
요약Following interleukin-5 stimulation, eosinophils rapidly become acorn-shaped. The bi-lobed nucleus is propelled to the cone of the acorn, termed the "nucleopod". By integrating eosinophil immunostaining with (phospho)proteomics data
Summary, Etc.  
요약Signal transducer and activator of transcription 3 (STAT3) is an important regulator of transcription in activated leukocytes. An unexpected STAT3 isoform peptide, lacking a single residue (Ser701) led to the questions, what are the relative pro
Summary, Etc.  
요약We describe the "LOCGEFs", a set of leukocyte-specific spliceforms of ARHGEF18, a guanine nucleotide exchange factor. These proteins were discovered because the proteomics dataset included peptides mapping to a protein annotated as LOC100996504.
Summary, Etc.  
요약Nance-Horan Syndrome-like protein 2 (NHSL2) was one of the most profoundly altered proteins after IL5 treatment: within 5 minutes, the fold-phosphorylation at 4 sites increased dramatically. Nearly nothing is published about this protein, so we
Subject Added Entry-Topical Term  
Biochemistry
Added Entry-Corporate Name  
The University of Wisconsin - Madison Biomolecular Chemistry
Host Item Entry  
Dissertation Abstracts International. 79-12B(E).
Host Item Entry  
Dissertation Abstract International
Electronic Location and Access  
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Control Number  
joongbu:554432
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