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Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2
Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2
- 자료유형
- 학위논문
- Control Number
- 0014999730
- International Standard Book Number
- 9780438271593
- Dewey Decimal Classification Number
- 574
- Main Entry-Personal Name
- Turton, Keren B.
- Publication, Distribution, etc. (Imprint
- [Sl] : The University of Wisconsin - Madison, 2018
- Publication, Distribution, etc. (Imprint
- Ann Arbor : ProQuest Dissertations & Theses, 2018
- Physical Description
- 263 p
- General Note
- Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
- General Note
- Adviser: Deane F. Mosher.
- Dissertation Note
- Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018.
- Summary, Etc.
- 요약Following interleukin-5 stimulation, eosinophils rapidly become acorn-shaped. The bi-lobed nucleus is propelled to the cone of the acorn, termed the "nucleopod". By integrating eosinophil immunostaining with (phospho)proteomics data
- Summary, Etc.
- 요약Signal transducer and activator of transcription 3 (STAT3) is an important regulator of transcription in activated leukocytes. An unexpected STAT3 isoform peptide, lacking a single residue (Ser701) led to the questions, what are the relative pro
- Summary, Etc.
- 요약We describe the "LOCGEFs", a set of leukocyte-specific spliceforms of ARHGEF18, a guanine nucleotide exchange factor. These proteins were discovered because the proteomics dataset included peptides mapping to a protein annotated as LOC100996504.
- Summary, Etc.
- 요약Nance-Horan Syndrome-like protein 2 (NHSL2) was one of the most profoundly altered proteins after IL5 treatment: within 5 minutes, the fold-phosphorylation at 4 sites increased dramatically. Nearly nothing is published about this protein, so we
- Subject Added Entry-Topical Term
- Biochemistry
- Added Entry-Corporate Name
- The University of Wisconsin - Madison Biomolecular Chemistry
- Host Item Entry
- Dissertation Abstracts International. 79-12B(E).
- Host Item Entry
- Dissertation Abstract International
- Electronic Location and Access
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- Control Number
- joongbu:554432