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Development of Trojan Horse Dimeric Inhibitors of P-Glycoprotein to Target HIV Reservoirs in the Brain
Contents Info
Development of Trojan Horse Dimeric Inhibitors of P-Glycoprotein to Target HIV Reservoirs in the Brain
자료유형  
 학위논문
Control Number  
0014999968
International Standard Book Number  
9780438361713
Dewey Decimal Classification Number  
540
Main Entry-Personal Name  
Agrawal, Neha.
Publication, Distribution, etc. (Imprint  
[Sl] : Purdue University, 2018
Publication, Distribution, etc. (Imprint  
Ann Arbor : ProQuest Dissertations & Theses, 2018
Physical Description  
210 p
General Note  
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
General Note  
Adviser: Jean A. Chmielewski.
Dissertation Note  
Thesis (Ph.D.)--Purdue University, 2018.
Summary, Etc.  
요약HIV/AIDS has emerged as an incredibly serious infectious disease. The complete eradication of HIV is hindered by virus reservoir formation in the host. Some of the locations of these reservoirs include the central nervous system (CNS), resting m
Summary, Etc.  
요약All the TH heterodimeric were found to inhibit P-gp mediated efflux of fluorescent substrates in T-cells as well as model blood-brain barrier cell lines. Two TH heterodimeric were found to inhibit HIV-1 replication in 12D7 cells most effectively
Subject Added Entry-Topical Term  
Chemistry
Subject Added Entry-Topical Term  
Organic chemistry
Subject Added Entry-Topical Term  
Biochemistry
Added Entry-Corporate Name  
Purdue University Chemistry
Host Item Entry  
Dissertation Abstracts International. 80-01B(E).
Host Item Entry  
Dissertation Abstract International
Electronic Location and Access  
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Control Number  
joongbu:553558
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