자료유형  

 학위논문

Control Number  

0014999963

International Standard Book Number  

9780438361652

Dewey Decimal Classification Number  

547

Main Entry-Personal Name  

Hostetler, Matthew A.

Publication, Distribution, etc. (Imprint  

[Sl] : Purdue University, 2018

Publication, Distribution, etc. (Imprint  

Ann Arbor : ProQuest Dissertations & Theses, 2018

Physical Description  

381 p

General Note  

Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.

General Note  

Adviser: Mark A. Lipton.

Dissertation Note  

Thesis (Ph.D.)--Purdue University, 2018.

Summary, Etc.  

요약The first part of this dissertation involves the rational design, synthesis and biological evaluation of small molecules targeting Class II HMGR. Inhibitors of this generation were designed based on information derived from the crystal structure

Summary, Etc.  

요약The second part of this dissertation summarizes our efforts to contribute new methods for the preparation of C-terminal modified and cyclic peptides on the solid-phase using the backbone amide linker (BAL) approach. To this end, an improved one-

Subject Added Entry-Topical Term  

Organic chemistry

Added Entry-Corporate Name  

Purdue University Chemistry

Host Item Entry  

Dissertation Abstracts International. 80-01B(E).

Host Item Entry  

Dissertation Abstract International

Electronic Location and Access  

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Control Number  

joongbu:553553